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Showing 1 to 12 of 4240 entries
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Paracrine mechanisms in adult stem cell signaling and therapy

adult

Gnecchi M.
GSID: 3bRojLFNqoMJ
M Gnecchi, Z Zhang, A Ni, VJ Dzau - Circulation research, 2008 - Am Heart Assoc

Animal and preliminary human studies of adult cell therapy following acute myocardial infarction have shown an overall improvement of cardiac function. Myocardial and vascular …

YliH (BssR) and YceP (BssS) Regulate Escherichia coli K-12 Biofilm Formation by Influencing Cell Signaling

k-12

Lee J, Wood TK.
GSID: v3ym6712onsJ
J Domka, J Lee, TK Wood - Applied and environmental …, 2006 - Am Soc Microbiol

… coli wild-type K-12 BW25113 and the isogenic strains with the yceP and yliH mutations were cultured overnight in LB glu medium (with kanamycin added to the two knockout mutants). The overnight cultures were then used to inoculate 250...

Method for recovery and immunoaffinity enrichment of membrane proteins illustrated with metastatic ovarian cancer tissues.

International journal of proteomics

Schneider LV, Likhte V, Wright WH, Chu F, Cambron E, Baldwin-Burnett A, Krakow J, Smejkal GB.
PMID: 22919487
Int J Proteomics. 2012;2012:838630. doi: 10.1155/2012/838630. Epub 2012 Jul 12.

Integral membrane proteins play key biological roles in cell signaling, transport, and pathogen invasion. However, quantitative clinical assays for this critical class of proteins remain elusive and are generally limited to serum-soluble extracellular fragments. Furthermore, classic proteomic approaches to...

Antibiotic resistance shaping multi-level population biology of bacteria.

Frontiers in microbiology

Baquero F, Tedim AP, Coque TM.
PMID: 23508522
Front Microbiol. 2013 Mar 06;4:15. doi: 10.3389/fmicb.2013.00015. eCollection 2013.

Antibiotics have natural functions, mostly involving cell-to-cell signaling networks. The anthropogenic production of antibiotics, and its release in the microbiosphere results in a disturbance of these networks, antibiotic resistance tending to preserve its integrity. The cost of such adaptation...

Lysophospholipids in retinal axon guidance: roles and cell signaling.

Neural regeneration research

Birgbauer E.
PMID: 26330827
Neural Regen Res. 2015 Jul;10(7):1067-8. doi: 10.4103/1673-5374.160091.

No abstract available.

Proteinases, Their Extracellular Targets, and Inflammatory Signaling.

Pharmacological reviews

Ramachandran R, Altier C, Oikonomopoulou K, Hollenberg MD.
PMID: 27677721
Pharmacol Rev. 2016 Oct;68(4):1110-1142. doi: 10.1124/pr.115.010991.

Given that over 2% of the human genome codes for proteolytic enzymes and their inhibitors, it is not surprising that proteinases serve many physiologic-pathophysiological roles. In this context, we provide an overview of proteolytic mechanisms regulating inflammation, with a...

S-Nitrosothiols: chemistry and reactions.

Chemical communications (Cambridge, England)

Zhang C, Biggs TD, Devarie-Baez NO, Shuang S, Dong C, Xian M.
PMID: 28944382
Chem Commun (Camb). 2017 Oct 12;53(82):11266-11277. doi: 10.1039/c7cc06574d.

The formation of S-nitrosothiols (SNO) in protein cysteine residues is an important post-translational modification elicited by nitric oxide (NO). This process is involved in virtually every class of cell signaling and has attracted considerable attention in redox biology. On...

Role of Mitogen-Activated Protein Kinases, Early Response Protooncogenes, and Activator Protein-1 in Cell Signaling by Asbestos.

Inhalation toxicology

Mossman B, Hubbard A, Shukla A, Timblin CR.
PMID: 26368630
Inhal Toxicol. 2000 Jan;12:307-16. doi: 10.1080/08958378.2000.11463240.

Cell signaling by pathogenic minerals may initiate the transactivation of genes that are critical to carcinogenesis and fibroproliferative diseases of the lung and pleura. We have shown previously that stimulation of the mitogen-activated protein kinase (MAPK) cascade by asbestos...

Cell Signaling in Mesothelial Cells by Asbestos: Evidence for the Involvement of Oxidative Stress in the Regulation of the Epidermal Growth Factor Receptor.

Inhalation toxicology

Faux SP, Houghton CE.
PMID: 26368632
Inhal Toxicol. 2000 Jan;12:327-36. doi: 10.1080/08958378.2000.11463242.

Asbestos has been shown to stimulate the mitogen-activated protein kinase signaling cascade after autophosphoryiation of the epidermal growth factor recptor (EGF-R), an event important in regulating the response of cells to extracellular signals. In studies reported here, we have...

Identification of molecular characteristics induced by radiotherapy in rectal cancer based on microarray data.

Oncology letters

Ge C, Wu M, Chen G, Yu G, Ji D, Wang S.
PMID: 28454466
Oncol Lett. 2017 Apr;13(4):2777-2783. doi: 10.3892/ol.2017.5750. Epub 2017 Feb 20.

The present study aimed to reveal the molecular characteristics induced by radiotherapy in rectal cancer at the transcriptome level. Microarray data (ID, GSE26027) downloaded from the Gene Expression Omnibus database were re-analyzed to identify differentially expressed genes (DEGs) between...

Reversible ratiometric detection of highly reactive hydropersulfides using a FRET-based dual emission fluorescent probe.

Chemical science

Kawagoe R, Takashima I, Uchinomiya S, Ojida A.
PMID: 28451253
Chem Sci. 2017 Feb 01;8(2):1134-1140. doi: 10.1039/c6sc03856e. Epub 2016 Sep 26.

Hydropersulfide (R-SSH) is an important class of reactive sulfur species (RSS) involved in a variety of physiological processes in mammals. A fluorescent probe capable of real-time detection of hydropersulfide levels in living cells would be a versatile tool to...

Effect of Statins on the Mortality of Bacteremic Patients: A Systematic Review and Meta-analysis of Clinical Trials.

North American journal of medical sciences

Shrestha P, Poudel DR, Pathak R, Ghimire S, Dhital R, Aryal MR, Mahmood M, Karmacharya P.
PMID: 27500129
N Am J Med Sci. 2016 Jun;8(6):250-1. doi: 10.4103/1947-2714.185034.

BACKGROUND: Statins modify inflammatory cell signaling during the immune response to infection. This has been considered as a pleotropic effect. Effects of statins in inflammatory conditions such as bacteremia have been found to be controversial.AIMS: We examined the effect...

Showing 1 to 12 of 4240 entries